赵育

编辑:系统管理员 | 阅读: 次 | 发布时间:2012-11-04

赵育:男,1976年生,副研究员,硕士研究生导师,1998年7月北京化工大学本科毕业;2004年7月中国海洋大学海洋化学专业硕士研究生毕业,获理学硕士学位,2007年7月中国海洋大学药物化学专业博士研究生毕业,获医学博士学位。2011年3月至2013年3月中国科学院上海药物研究所博士后,2014年11月至2015年11月美国威斯康辛麦迪逊大学药学院访问学者。现为中国药学会会员,主要从事药物化学和糖化学研究,近五年主持省、市厅级课题3项,参与国家自然科学基金2项。
通讯作者及第一作者文章(2011-2015):
1. Yu Zhao, Cun Wang Ge, Li Zhu*, Synthesis and Evaluation of Aroylthiourea Derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as Novel Topoisomerase II Inhibitors , European Journal of Medicinal Chemistry. 2011, 46, 901-906
2.Yu Zhao, Chengniu Wang, Li Zhu*, Synthesis and Antitumor Activity of Novel Aroylthiourea Derivatives of Podophyllotoxin, Investigational New Drugs, 2012, 30, 17-24
3. Yu Zhao, Chunyan Ni, Yuting Zhang, Li Zhu, Synthesis and Bioevaluation of Diphyllin Glycosides as Novel Anticancer Agents, Archiv der Pharmazie. 2012, 345, 622–628
4. Yu Zhao, Jie Hui, Li Zhu, Synthesis and Bioevaluation of Novel Arylnaphthalene Lignans as Anticancer Agents, Medicinal Chemistry Research., 2013, 22: 2505–2510
5. Yu Zhao, Zhonghua Wu, Yuting Zhang, Li Zhu*, HY-1 induce G2/M cell cycle arrest in human colon cancer cells via ATR-Chk1-Cdc25C and Weel pathways, Cancer Science, 2013,104 (8): 1062-1066
6. Zhitao Zhang, Jinlong Ma, Li Zhu, Yu Zhao*, Synthesis and identification of cytotoxic diphyllin glycosides as vacuolar H+-ATPase inhibitors, European Journal of Medicinal Chemistry, 2014,82, 466-471
7. Xiaodong Zhao, Qiu Tan, Zhitao Zhang, Yu Zhao*, 1,3,5-Triazine inhibitors of histone deacetylases: synthesis and biological activity, Medicinal Chemistry Research., 2014, 23:5188–5196
8. Yu Zhao, Yapeng Lu, Jinlong Ma, Li Zhu*, Synthesis and Evaluation of Cleistanthin-A Derivatives As Potent Vacuolar H+-ATPase Inhibitors., 2015, Chemical Biology and Drug Design, 2015, 86, 691-696.
9. Yu Zhao, Rui Zhang, Yapeng Lu, Jinlong Ma, Li Zhu*, Synthesis and bioevaluation of heterocyclic derivatives of Cleistanthin-A, Bioorganic & Medicinal Chemistry 2015, 23, 4884–4890
10. 马金龙,翟艳光,朱俐,赵育*,AgOTf 催化的一锅法合成 1-(1H-吡咯-3-基)-1,2-二氢异喹啉衍生物,有机化学,2015, 35, 2366-2371
11. Wangze Song, Yu Zhao*, John C. Lynch, Hyunjin Kim and Weiping Tang*, Divergent de novo synthesis of all eight stereoisomers of 2,3,6-trideoxyhexopyranosides and their oligomers, Chem. Commun., 2015, 51, 17475-17478