杨叶伟 博士

编辑:系统管理员 | 阅读: 次 | 发布时间:2011-10-11

杨叶伟:男,1980年3月生,副研究员。2003年6月浙江大学化学专业本科毕业,获工学学士学位,2003年9月浙江大学有机合成专业硕博连读,2008年7月博士研究生毕业,获理学博士学位。2008.7-2014.6,任职于浙江省医学科学院,副研究员,主要从事生物制药、新药研发药物化学研究。主持国家自然科学青年基金、省、厅研究项目及新药研发课题6近五年第一作者发表的论文代表作:

1.Piperidine Nucleophilic Substitution Without Solvent: An Efficient Synthesis of Raloxifene Synthetic Communications, 44(22), pp 3271-3276, 2014/11/17.

2.Synthesis of 2-phenylbenzofuran derivatives and selective binding activities on estrogen receptor Chem. Pharm. Bull. (Tokyo). 2012, 60, 270.

3.Halohydroxylation of alkylidenecyclopropanes using N-halosuccinimide (NXS) as the halogen source: an efficient synthesis of halocyclopropylmethanol and 3-halobut-3-en-1-ol derivatives Tetrahedron Lett. 2009, 50, 5754-5756.

4. Iodohydroxylation of Methlenecyclopropanes. An Efficient Synthesis of Iodocyclopropyl-methanol and 3-Iodo-but-3-en-1-ol derivativesJ. Org. Chem. 2008, 73, 4702.

5.Intramolecular Cycloisomerization of Aryl-Substituted Alkylidenecyclopropanes via NHC Palladium-Catalyzed Cascade C–C Bond Cleavage/C–H Activation/ C–C Bond Formation

Synlett. 2008, 9, 1366.

Acylation of Alkylidenecyclopropanes for the Facile Synthesis of α,β –Unsaturated Ketone and Benzofulvene Derivatives with High Stereoselectivity Org. Lett. 2007, 9, 1667.

6.A Novel Synthesis of Spiro[imidazolidine-2, 3’-benzo[b]thiophene] by One-Pot Reaction of Arynes, Aryl Isothiocyanates and N-heterocyclic CarbenesSynlett, 2007, 10, 1533.

7.Study On the Electrophilic Tellurolactonization of 1,2-Allenic Phosphonates: A Facile and Efficient Synthesis of 4-(Phenyltelluro)-1,2-oxaphosphol-3-ene 2-Oxides

Yuan, Jingqi; Ruan, Xiuxiu; Yang, Yewei; Huang, Xian* Synlett, 2007, 18, 2871.

8.Thiazolium-Mediated Multicomponent Reactions: A Facile Synthesis of 3-AminofuranDerivatives Org. Lett. 2005, 7, 1343.