药物制剂系

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方桂花

作者:金飞     日期:2021-10-26   点击数:45  

师资介绍

方桂花,女, 1990年9生,药剂学博士,南通大学药学院,讲师


研究方向:

口服递药,眼部新型给药系统,缓控释制剂


基金项目:

  1. 南通市自然科学基金,JC2019100,基于胆酸吸收途径的口服纳米递药系统构建及治疗肝癌的研究,2019-07 2021-063万元,已结题,主持

  2. 江苏省高校自然科学研究面上项目18KJB350009粘附性高载药量脂质载体应用于胰岛素口服传递研究2018-07 2020-063万元,已结题,主持

  3. 江苏省自然科学基金(青年项目)BK20170445,靶向新型有机阳离子转运体的眼用前药递送系统的研究, 2017-07 2020/0620万,已结题,参加


代表性论文:

(1) Fang Guihua and Tang Bo*, Current advances in nano-delivery of celastrol for treating inflammation associated diseases, Journal of Materials Chemistry B, 2020, 8(48), 10954-10965.

(2) Fang Guihua, Tang Bo*, Advanced delivery strategies facilitating oral absorption of heparins, Asian Journal of Pharmaceutical Sciences, 2020, 15(4), 449-460.

(3)Tang Bo, Qian Yu, Fang Guihua*. Development of Lipid-Polymer Hybrid Nanoparticles for Improving Oral Absorption of Enoxaparin. Pharmaceutics, 2020, 12(7), 607-618.

(4) Tang Bo, Qian Yu, Gou Yi, Cheng Gang, Fang Guihua*, VE-Albumin Core-Shell Nanoparticles for Paclitaxel Delivery to Treat MDR Breast Cancer. Molecules, 2018, 23, 2760.

(5) Fang Guihua, Zhou Jing, Qian Yu, Gou Jingxin, Yang Xiang, Tang Bo*, Development and evaluation of thermo-sensitive hydrogel system with nanocomplexes for prolonged subcutaneous delivery of enoxaparin, Journal of Drug Delivery Science and Technology, 2018, 48 (2018), 118-124.

(5) Fang Guihua, Tang Bo, Chao Yanhui,  Xu Helin, Gou Jingxin, ZhangYu, Xu Hui, Tang Xing*,Cysteine-functionalized nanostructured lipid carriers for oral delivery of docetaxel: A permeability and pharmacokinetic study. Molecular Pharmaceutics, 2015, 12 (7), 2384-2395.

(6) Fang Guihua, Tang Bo, Chao Yanhui, Zhang Yu*, Xu Hui, Tang Xing*, Improved oral bioavailability of docetaxel by nanostructured lipid carriers: in vitro characteristics, in vivo evaluation and intestinal transport studies. RSC Advances, 2015, 5(117), 96437-96447.

(7) Fang Guihua, Tang Bo, Liu Zitong, Gou Jingxin, ZhangYu, Xu Hui, Tang Xing*. Novel hydrophobin-coated docetaxel nanoparticles for intravenous delivery: in vitro characteristics and in vivo performance. European Journal of Pharmaceutical Sciences, 2014, 60, 1-9.