方桂花
方桂花简历
方桂花，女，药剂学博士，南通大学药学院，讲师。
教育经历
2012-09至2016-06：沈阳药科大学药剂学博士
2008-09至2012-06：沈阳药科大学基础药学基地班学士
工作经历
2016-07至今：南通大学药学院，讲师
研究方向
口服递药，眼部新型给药系统，缓控释制剂
基金项目
1.国家自然科学基金青年基金，82404544，基于“三位一体”策略构建眼部高效递药系统治疗湿性老年黄斑变性的研究，2025-01至2027-12，30万元，主持
2.南通市自然科学基金，JC2019100，基于胆酸吸收途径的口服纳米递药系统构建及治疗肝癌的研究，2019-07至2021-06，3万元，已结题，主持
3.江苏省高校自然科学研究面上项目，18KJB350009，粘附性高载药量脂质载体应用于胰岛素口服传递研究，2018-07至2020-06，3万元，已结题，主持
代表性论文
(1)Bo Tang, Qiuxiang Wang, Guowei Zhang, Aiwen Zhang, Lu Zhu, Rongrong Zhao, Hongwei Gu, Jie Meng, Junfang Zhang* & Guihua Fang* OCTN2 and ATB0,+ targeted nanoemulsions for improving ocular drug delivery,Journal of Nanobiotechnology, 130 (2024), 2024.
(2) Wang Qiuxiang; Zhang Aiwen; Zhu Lu; Yang Xuewen;Fang Guihua*; Tang Bo*, Cyclodextrin-based ocular drug delivery systems: A comprehensive review,Coordination Chemistry Reviews, 476 (2023),214919-214943.
(3) Tang Bo, Yang Xuewen, Zhang Aiwen, Wang Qiuxiang, Fan Lei andFang Guihua*, Polypseudorotaxane hydrogel based on Tween 80 and α-cyclodextrin for sustained delivery of low molecular weight heparin,Carbohydrate Polymers, 297 (2022), 120002-120012.
(4)Yang Xuewen, Wang Qiuxiang, Zhang Aiwen, Shao Xinyao, Liu Tianqing, Tang Bo* andFang Guihua*,Strategies for sustained release of heparin: A review,Carbohydrate Polymers, 294 (2022), 119793-119806.
(5)Fang Guihua, Yang Xuewen, Chen Sumeng, Wang Qiuxiang, Zhang Aiwen and Tang Bo*, Cyclodextrin-based host-guest supramolecular hydrogels for local drug delivery,Coordination Chemistry Reviews, 2022,454(2022), 214352.
(6)Fang Guihua, Wang Qiuxiang, Yang Xuewen, Qian Yu, Zhang Guowei and Tang Bo*, γ-cyclodextrin-based polypseudorotaxane hydrogels for ophthalmic delivery of flurbiprofen to treat anterior uveitis,Carbohydrate Polymers, 2022,277(1), 118889.
(7)Fang Guihua, Wang Qiuxiang, Yang Xuewen, Qian Yu, Zhang Guowei, Zhu Qiang and Tang Bo*, Vesicular phospholipid gels as topical ocular delivery system for treatment of anterior uveitis,Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2021,627(2021),127187.
(8)Fang Guihua, Yang Xuewen, Wang Qiuxiang, Zhang Aiwen and Tang Bo*, Hydrogels-based ophthalmic drug delivery systems for treatment of ocular diseases,Materials Science and Engineering: C, 2021, 127(2021),112212.
(9)Fang Guihua and Tang Bo*, Current advances in nano-delivery of celastrol for treating inflammation-associated diseases, Journal of Materials Chemistry B, 2020,8(48), 10954-10965.
(10)Fang Guihua, Tang Bo*, Advanced delivery strategies facilitating oral absorption of heparins,Asian Journal of Pharmaceutical Sciences, 2020, 15(4), 449-460.
(11) Tang Bo, Qian Yu,Fang Guihua*. Development of Lipid-Polymer Hybrid Nanoparticles for Improving Oral Absorption of Enoxaparin. Pharmaceutics, 2020, 12(7), 607-618.