药物制剂系

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郑孝华

作者:金飞     日期:2023-10-11   点击数:2493  

郑孝华,男,汉族,19894月生,副教授,硕士研究生导师

教育经历:

2010.09-2014.06湖北大学,应用化学,学士

2014.09-2019.11中国科学技术大学,高分子化学与物理,博士

工作经历:

2020.09-至今 南通大学,药学院,副教授

研究方向:

肿瘤成像以及治疗,光动力治疗,光热治疗

主持或参与项目:

1.国家自然科学青年基金,四氢卟吩基共价有机骨架材料的尺寸、形貌调控及生物医学应用,2022-012024-1230万元,主持

2.横向课题,一种光活性增强的新型光敏剂的技术研发,3万,主持

科研成果:

在光动力或者光热治疗领域,以第一作者及参与作者已发表十余篇SCI论文。

代表性论文:

(1) Wu, J.; Rao, M.; Zhu, Y.; Wang, P.; Chen, M.; Qu, Y.; Zheng, X.; Jiang, Y. A NIR-II absorbing conjugated polymer based on tetra-fused isoindigo with ultrahigh photothermal conversion efficiency for cancer therapy.Chemical Communications2024,60 (64), 8427-8430, 10.1039/D4CC02546F. DOI: 10.1039/D4CC02546F.

(2) Wu, J.; Shi, Y.; Zhou, M.; Chen, M.; Ji, S.; Liu, X.; Zhou, M.; Xia, R.; Zheng, X.; Wang, W. Nutrient vitamins enabled metabolic regulation of ferroptosis via reactive oxygen species biology.Frontiers in Pharmacology2024,15, DOI: 10.3389/fphar.2024.1434088.

(3) Shi, Y.; Zou, Y.; Khan, M. S.; Zhang, M.; Yan, J.; Zheng, X.; Wang, W.; Xie, Z. Metal–organic framework-derived photoelectrochemical sensors: structural design and biosensing technology.Journal of Materials Chemistry C2023,11 (11), 3692-3709, 10.1039/D2TC05338A. DOI: 10.1039/D2TC05338A.

(4) Wang, W.; Yu, Y.; Jin, Y.; Liu, X.; Shang, M.; Zheng, X.; Liu, T.; Xie, Z. Two-dimensional metal-organic frameworks: from synthesis to bioapplications.Journal of Nanobiotechnology2022,20 (1), 207. DOI: 10.1186/s12951-022-01395-9.

(5) Zheng, X.; Jin, Y.; Liu, X.; Liu, T.; Wang, W.; Yu, H. Photoactivatable nanogenerators of reactive species for cancer therapy.Bioactive Materials2021,6 (12), 4301-4318.

(6) Zheng, X.; Wang, L.; Guan, Y.; Pei, Q.; Jiang, J.; Xie, Z. Integration of metal-organic framework with a photoactive porous-organic polymer for interface enhanced phototherapy.Biomaterials2020,235, 119792.

(7) Zheng, X.; Wang, L.; Liu, M.; Lei, P.; Liu, F.; Xie, Z. Nanoscale Mixed-Component Metal–Organic Frameworks with Photosensitizer Spatial-Arrangement-Dependent Photochemistry for Multimodal-Imaging-Guided Photothermal Therapy.Chemistry of Materials2018,30 (19), 6867-6876. DOI: 10.1021/acs.chemmater.8b03043.