天然药物系

首页  师资队伍  在职教师  天然药物系

李金龙

作者:金飞     日期:2021-10-26   点击数:30  

师资介绍


姓名李金龙

性别

民族汉族

出生年月1988.07

职称副教授

学历博士

职务

研究方向:天然药物化学

社会学术兼职:

基金项目:

塞内加尔美登木降糖活性物质基础及作用机制研究,81803384,国家自然科学基金委,21万,21万,2019.01 ~ 2021.12,李金龙

塞内加尔美登木降糖活性物质的发现及其作用机制研究,BK20180947,江苏省科技厅,20万,20万,2018.07 ~ 2021.06,李金龙

中药隔山消中抗老年痴呆活性成分的发现研究,SIMM1705KF-04,新药研究国家重点实验室,8万,8万,2017.05 ~ 2018.04,李金龙

江苏道地药材滨海白首乌根皮抗衰老活性成分的研究,18KJB360013,江苏省教育厅,3万,3万,2018.09 ~ 2020.08,李金龙

江苏道地药材滨海白首乌根皮中抗老年痴呆成分的研究,MS12017021-2,南通市科技局,2万,2万,2017.06 ~ 2019.05,李金龙


科研成果

代表性论文

[1]Ge X1, Jiang H1, Li J*. Rapid continuous photoflow synthesis of naturally occurring arylnaphthalene lignans and their analogs. Natural Product Research. 2021 Apr 21:1-5.

[2] Chen S1, Tsang NY1, Jiang H1, Zhang H, Ge X, Wu Y, Shen Y, Xie W, Li J*. Cytotoxic tigliane diterpenoids from Euphorbia neorubella. Natural Product Research. 2021 Apr 29:1-5.

[3] Duan YN1, Ge X1, Jiang HW, Zhang HJ, Zhao Y, Li JL*, Zhang W*, Li JY*. Diphyllin Improves High-Fat Diet-Induced Obesity in Mice Through Brown and Beige Adipocytes. Frontiers in endocrinology. 2020;11.

[4] Zhu G1, Liu Y1, Zhi Y, Jin Y, Li J*, Shi W, Liu Y, Han Y, Yu S, Jiang J*, Zhao X*. PKA-and Ca2+-dependent p38 MAPK/CREB activation protects against manganese-mediated neuronal apoptosis. Toxicology letters. 2019 Jul 1;309:10-9.

[5] Jiang HW1, Gu SS1, Cao L1, Jiang SS, Lin J, Chen Y, Wang L, Jiao H, Li JY*, Zhao WM*, Li JL*. Potential hypoglycemic effect of acetophenones from the root bark of Cynanchum wilfordii. Natural product research. 2019 Aug 18;33(16):2314-21.

[6] Wang LN, Jiang HW,Li JL*, Li JY*. Enhancement of glucose utilization by loesenerine through AMPK activation in myotubes. Chemical and Pharmaceutical Bulletin. 2018 Sep 1;66(9):885-6.

[7] Jiang HW, Lin J, Wang GM, Zhang JJ, Gu SS, Cao L, Chen Y, Wang L, Jiao H, Zhu WL, Zhang HY*, Zhao WM*, Li JL*. Acetophenone derivatives from the root bark of Cynanchum wilfordii as potential neuroprotective agents. Phytochemistry Letters. 2018 Apr 1;24:179-83.

[8] Qin JJ1, Mao YY1,Li JL1, Guan Y*, Zhao WM*. Aromatic monoterpenoid glycosides from the seeds of Paeonia ostii. Journal of Asian natural products research. 2017 Dec 2;19(12):1149-54.

[9]Li JL1, Wu L1, Wu J1, Feng HX, Wang HM, Fu Y, Zhang RJ, Zhang HY*, Zhao WM*. Caffeoyl triterpenoid esters as potential anti-ischemic stroke agents from Celastrus orbiculatus. Journal of natural products. 2016 Nov 23;79(11):2774-9.

[10]Li JL, Gao ZB, Zhao WM. Identification and evaluation of antiepileptic activity of C21 steroidal glycosides from the roots of Cynanchum wilfordii. Journal of natural products. 2016 Jan 22;79(1):89-97.

[11] Yu BW1, Li JL1, Guo BB, Fan HM, Zhao WM, Wang HY. Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H 2 O 2-induced apoptosis. Acta Pharmacologica Sinica. 2016 Nov;37(11):1413-22.

[12]Li JL1, Gao LX1, Meng FW1, Tang CL, Zhang RJ, Li JY, Luo C*, Li J*, Zhao WM*. PTP1B inhibitors from stems of Angelica keiskei (Ashitaba). Bioorganic & medicinal chemistry letters. 2015 May 15;25(10):2028-32.

[13]Li JL1, Zhou J1, Chen ZH, Guo SY, Li CQ, Zhao WM. Bioactive C21 steroidal glycosides from the roots of Cynanchum otophyllum that suppress the seizure-like locomotor activity of zebrafish caused by pentylenetetrazole. Journal of natural products. 2015 Jul 24;78(7):1548-55.

[14]Li JL, Fu Y, Zhang HY*, Zhao WM*. Two new humulanolides from the roots of Cynanchum wilfordii. Tetrahedron letters. 2015 Nov 18;56(46):6503-5.