王雯丽

师资介绍

王雯丽，女，汉族，1989年12月生，博士，讲师，硕士生导师。

教育经历：

2008.09-2012.06河南中医药大学，药学，学士

2012.09-2015.06沈阳药科大学，天然药物化学，硕士

2016.09-2020.06中国药科大学，中药学，博士

工作经历：

2015.07-2015.11浙江大学，药学，研究助理

2020.09-至今 南通大学，药学院，讲师

研究方向：

中药化学，活性天然产物

社会学术兼职：

    1、天津中草药杂志社《中草药》第三届青年编委；

2、中华中医药会员中药化学分会第五届青年委员；

3、《亚洲传统医药杂志》第一届青年编委。

基金项目：

国家自然科学基金委员会,青年科学基金项目, 32100317,联合生物合成途径与LC-MS策略的新颖萜类聚合物的发现及α-葡萄糖苷酶抑制活性研究, 2022-01-01至2024-12-31, 30万元,在研,主持

科研成果：

主要从事杉科植物萜类聚合物的研究工作，对萜类以及萜类聚合物结构解析和活性有较深入的研究工作，目前已发现多个新颖骨架类化合物，其中一个被NPR评为热点化合物，主要研究成果已发表SCI论文10余篇，主要发表在Chinese Chemical Letters, Chemical Communications，Organic Chemistry Frontiers，Journal of Natural Products等天然产物主流期刊上，并以此为基础获得国家青年科学基金项目一项。

代表性论文：

[1] Y. Wang, P. Tang, W. Tu, Q. Gao, C. Wang, L. Tan, L. Zhao, H. Han, L. Ma, K. Otsuki, W. Xiao,W. L. Wang*, J. Liu, Y. Li, Z. Zhan, W. Li, X. Zhou, N. Li, Highly anticipated natural diterpenoids as an important source of new drugs in 2013–2023,Chinese Chemical Letters (2024).

[2]W. L. Wang, D. R. Zhu, L. N. Li, X. Q. Liu, L. Zhu, T. Y. Zhu, C. Chen, C. Han, P. Ying, Z. H. Lin, J. G. Luo, L. Y. Kong, Bioactive Dimeric Diterpenoids fromTaiwania cryptomerioides (Hayata) and Their Biological Activities, Chemistry Biodiversity (2023) e202201067.

[3]W. L. Wang, K. Y. Zhang, M. Q. Yuan, M. Yang, A. D. Wang, L. Huang, J. L. Li, α-Glucosidase inhibitors from the husks of rice Oryza sativa L,Fitoterapia 171 (2023).

[4] X. Jiang, X. H. Zhang, Y. X. Li, K. Chen, B. Lin, T. Q. Lu, M. Yang, G. T. Chen, B. Y. Fan,W. L. Wang, Chemical constituents from the leaves ofCinnamomum camphora and their α-glucosidase inhibitory activities,Phytochemistry Letters 57 (2023) 101-105.

[5] W. L. Wang, Y. Li, Y. He, X. Jiang, Y. Yi, X. Zhang, S. Zhang, G. Chen, M. Yang, J.-L. Luo, B. Fan, Progress in the total synthesis of resin glycosides,Frontiers in Chemistry 10 (2022).

[6] Y. Lu, Y. Tang, Y. Wu, X. Zhang, Y. Yi,W. L. Wang*, A. Wang, M. Yang, B. Y. Fan, G. Chen, Microbial transformation of betulonic acid by Circinella muscae CGMCC 3.2695 and anti-neuroinflammatory activity of the products,Phytochemistry (2022) 113431.

[7]W. L. Wang, X. Q. Liu, D. R. Zhu, C. Chen, L. J. Gong, J. M. Zhu, T. Y. Zhu, J. G. Luo, L. Y. Kong, Taxodinoids A-D, four heptacyclic C40 diterpene dimers from the seeds ofTaxodium distichum,Tetrahedron (2021).

[8]W. L. Wang, X. Q. Liu, M. H. Zhang, B. Lin, D. R. Zhu, L. N. Li, C. Chen, C. Han, J. G. Luo, L. Y. Kong, Taxodisones A and B: bioactive C₃₀-terpenes with new skeletons fromTaxodium distichum and their biosynthetic origin,Chemical Communications56 (2020) 3329-3332.

[9]W. L. Wang, Y. Z. Tang, Y. X. Liu, L. Yuan, J. Wang, B. Lin, D. Zhou, L.Sun, R. B. Huang, G. Chen, N. Li, Isolation, structure elucidation, and synthesis of (±)-millpuline A with a suppressive effect in miR-144 expression,Organic Chemistry Frontiers2019, 6, 2850–2859.

[10]W. L. Wang, D.R. Zhu, C. Chen, T.Y. Zhu, C. Han, F.Y. Liu, L.N. Li, J.G. Luo, L.Y. Kong, Taicrypnacids A and B, a Pair of C37 Heterodimeric Diterpenoid Stereoisomers fromTaiwania cryptomerioides, J Nat Prod 82(8) (2019) 2087-2093.

[11]W. L. Wang, D. R. Zhu, J. Luo, F. Y. Liu, C. Chen, T. Y. Zhu, L. N. Li, C. Han, J. G. Luo, L. Y. Kong,  Taiwanoids A–D, four dimeric diterpenoids featuring tetracyclic [7. 7^{5, 9}.4.0^{5, 10}.0^{8, 9}] octodecane fromTaiwania cryptomerioidesim,Organic & Biomolecular Chemistry16 (2018) 9059–9063.