天然药物系

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王雯丽

作者:金飞     日期:2023-11-02   点击数:2130  

师资介绍


姓名王雯丽    

性别女  

民族

出生年月1989.12   

职称讲师       

学历博士

职务:无

研究方向中药活性成分研究

社会学术兼职中华中医药学会中药化学分会青年委员;《中草药》第三届青年编委。

基金项目

国家青年基金:联合生物合成途径与LC-MS策略的新颖萜类聚合物的发现及α-葡萄糖苷酶抑制活性研究(32100317

科研成果:

代表性论文

1.Wang, W. L.;  Zhu, D. R.;  Li, L. N.;  Liu, X. Q.;  Zhu, L.;  Zhu, T. Y.;  Chen, C.;  Han, C.;  Ying, P.;  Lin, Z. H.;  Luo, J. G.; Kong, L. Y., Bioactive Dimeric Diterpenoids from Taiwania cryptomerioides (Hayata) and Their Biological Activities. Chem Biodivers 2023, e202201067.

2.Jiang, X.;  Zhang, X.-H.;  Li, Y.-X.;  Chen, K.;  Lin, B.;  Lu, T.-Q.;  Yang, M.;  Chen, G.-T.;  Fan, B. Y.; Wang, W. L.*, Chemical constituents from the leaves of Cinnamomum camphora and their α-glucosidase inhibitory activities. Phytochemistry Letters 2023, 57, 101-105.

3.Wang, W. L.;  Li, Y.;  He, Y.;  Jiang, X.;  Yi, Y.;  Zhang, X.;  Zhang, S.;  Chen, G.;  Yang, M.;  Luo, J.-L.; Fan, B., Progress in the total synthesis of resin glycosides. Frontiers in Chemistry 2022, 10.

4.Lu, Y.;  Tang, Y.;  Wu, Y.;  Zhang, X.;  Yi, Y.;  Wang, W. L.*;  Wang, A.;  Yang, M.;  Fan, B.; Chen, G., Microbial transformation of betulonic acid by Circinella muscae CGMCC 3.2695 and anti-neuroinflammatory activity of the products. Phytochemistry 2022, 113431.

5.Wang, W. L.;  Liu, X.-Q.;  Zhu, D.-R.;  Chen, C.;  Gong, L.-J.;  Zhu, J.-M.;  Zhu, T.-Y.;  Luo, J.-G.; Kong, L.-Y., Taxodinoids A-D, four heptacyclic C40 diterpene dimers from the seeds of Taxodium distichum. Tetrahedron 2021.

6.Wang, W. L.;  Liu, X.-Q.;  Zhang, M.-H.;  Lin, B.;  Zhu, D.-R.;  Li, L.-N.;  Chen, C.;  Han, C.;  Luo, J.-G.; Kong, L.-Y., Taxodisones A and B: bioactive C30-terpenes with new skeletons from Taxodium distichum and their biosynthetic origin. Chemical Communications 2020, 56, 3329-3332.

7.Wang, W. L.; Tang, Y. Z.; Liu, Y. X., L.; Yuan, L.; Wang, J.; Lin, B.; Zhou, D.;  Sun, L.; Huang, R. B.; Chen, G.; Li, N., Isolation, structure elucidation, and synthesis of (±)-millpuline A with a suppressive effect in miR-144 expression. Organic Chemistry Frontiers 2019.

8.Wang, W. L.; Zhu, D. R.; Chen, C.; Zhu, T. Y.; Han, C.; Liu, F. Y.; Li, L. N.;  Luo, J. G.; Kong, L. Y., Taicrypnacids A and B, a Pair of C37 Heterodimeric Diterpenoid Stereoisomers from Taiwania cryptomerioides. J Nat Prod 2019, 82 (8), 2087-2093.

9.Wang, W. L.; Zhu, D. R.; Luo, J.; Liu, F. Y..; Chen, C.; Zhu, T. Y.; Li, L. N.;  Han, C.; Luo, J. G.; Kong, L. Y., Taiwanoids A–D, four dimeric diterpenoids featuring tetracyclic [7. 75, 9.4.05, 10.08, 9] octodecane from Taiwania cryptomerioidesim. Organic & Biomolecular Chemistry 2018, 16, 9059–9063

10.Wang, W. L.; Li, N.; Wang, J.; Chen, G.; Huang, R. B.; Zhao, W. H.; Li, J. Y.; Si, Y. Y., Bioactive benzofuran-chalcanes as potential NQO1 inducers from Millettia pulchra (Benth) kurzvar-laxior (Dunn) Z.Wei. Phytochemistry 2016, 131, 107-114.

11.Wang, W. L.; Wang, J.; Li, N.; Zhang, X. R.; Zhao, W. H.; Li, J. Y.; Si, Y. Y., Chemopreventive flavonoids from Millettia pulchra Kurz var-laxior (Dunn) Z.Wei (Yulangsan) function as Michael reaction acceptors. Bioorganic & Medicinal Chemistry Letters 2015, 25 (5), 1078-1081.