徐丽星

师资介绍

徐丽星，女，汉族，1988年11月生，理学博士，讲师。主要从事中药活性成分治疗脑病作用机制及药物靶向策略研究。

教育工作经历：

2019.09-至今 南通大学，药学院，讲师

2016.09-2019.06中国药科大学，中药学，博士

2015.07-2016.08南京瑞鹰润泽医药有限公司，科研助理

2012.09-2015.06中国药科大学，中药学，硕士

2007.09-2012.06合肥师范学院，化学，学士

基金项目：

1. 国家自然科学基金青年项目，黄芩及黄芩苷基于Rho/ROCK调节线粒体动态改善糖尿病脑病的作用及机制研究，2018/01-2020/12，20万元，结题，参与

2. 国家自然科学基金面上项目，黄芩和黄芩苷基于离子通道调控神经干细胞分化的抗抑郁机制研究，2015/01-2019/12，60万元，结题，参与

代表性论文：

1. Lixing Xu; Jie Yang; Xinyu Cao; Jiayi Chen; Zhikuan Liu; Liangliang Cai*; Yanyan Yu*; Haiqin Huang*. Sequential system based on ferritin delivery system and cell therapy for modulating the pathological microenvironment and promoting recovery.International Journal of Pharmaceutics, 2024, 664: 124607.

2. Xinyu Cao; Bingyu Wu; Jiayi Chen; Zhikuan Liu; Yang Yang; Shanshan Li; Hongyan Zhu;Lixing Xu*; Haiqin Huang*. Hydroxypropyl Cellulose-Based Orally Dissolving Film Loaded with Insoluble Dexamethasone for Treatment of Oral Ulcers.Molecular Pharmaceutics, 2024, 21: 4012-4023.

3. Dan Sun; Xiao Du; Xinyu Cao; Bingyu Wu; Shanshan Li; Yongmei Zhao; Tianqing Liu;Lixing Xu*; Haiqin Huang*. Neutrophil-Based Bionic Delivery System Breaks Through the Capillary Barrier of Liver Sinusoidal Endothelial Cells and Inhibits the Activation of Hepatic Stellate Cells.Molecular Pharmaceutics, 2024, 21: 2043-2057.

4. Tao Yang; Xiao Du;Lixing Xu*. Radioprotective effect of Ginkgolide B on brain: The mediating role of DCC/MST1 signaling, International Journal of Radiation Biology, 2023, 7: 1-33.

5. Dan Sun; Shanshan Li; Haiqin Huang;Lixing Xu*. Neurotoxicity of melittin: Role of mitochondrial oxidative phosphorylation system in synaptic plasticity dysfunction, Toxicology,2023, 10(153628): 497-498.

6. Lixing Xu; Xiao Du; Yao Zhou; Xinyu Cao; Ying Shen; Hongyan Zhu*; Haiqin Huang*. Polyaspartic Acid-Stabilized CaCO₃-Containing In Situ Hydrogel for Protection and Treatment of Gastric Ulcer.Molecular Pharmaceutics, 2023, 20: 2105-2118.

7. Lixing Xu; Enhe Bai; Yangbo Zhu; Jiayi Qin; Xiao Du*; Haiqin Huang*. pH-Responsive Hydrogel as a Potential Oral Delivery System of Baicalin for Prolonging Gastroprotective Activity. Pharmaceutics, 2023, 15, 257.

8. Lixing Xu; Haiqin Huang; Tianqing Liu; Tao Yang*; Xuan Yi*; Exposure to X-rays Causes Depression-like Behaviors in Mice via HMGB1-mediated Pyroptosis, Neuroscience, 2022, 481: 99-110.

9. Lixing Xu; Jing Su; Liting Guo; Siqi Wang; Xueyang Deng*; Shiping Ma*. Modulation of LPA1 receptor-mediated neuronal apoptosis by saikosaponin-d: a target involved in depression, Neuropharmacology, 2019, 155: 150-161

10. Lixing Xu; zhouye Ji; Liting Guo; Ruyi Zhang; Rong Qu*; Shiping Ma*; Saikosaponin-Dmediated downregulation of neurogenesis results in cognitive dysfunction by inhibiting Akt/Foxg-1 pathway in mice, Toxicology Letters, 2018, 284: 79-85.

11. Lixing Xu, Yuebi Li, Qiang Fu*, Shiping Ma*. Perillaldehyde attenuates cerebral ischemia–reperfusion injury-triggered overexpression of inflammatory cytokines via modulating Akt/JNK pathway in the rat brain cortex. Biochemical and Biophysical Research Communications, 2014, 454: 65-70.