王雯丽

师资介绍

王雯丽，女，汉族，1989年12月生，博士，副教授，硕士生导师。

教育经历：

2008.09-2012.06河南中医药大学，药学，学士

2012.09-2015.06沈阳药科大学，天然药物化学，硕士

2016.09-2020.06中国药科大学，中药学，博士

工作经历：

2015.07-2015.11浙江大学，药学，研究助理

2020.09-至今 南通大学，药学院，讲师

研究方向：

中药化学，活性天然产物

社会学术兼职：

1、天津中草药杂志社《中草药》第四届青年编委；

2、中华中医药会员中药化学分会第五届青年委员；

基金项目：

1.国家自然科学基金委员会,青年科学基金项目, 32100317,联合生物合成途径与LC-MS策略的新颖萜类聚合物的发现及α-葡萄糖苷酶抑制活性研究, 2022-01-01至2024-12-31, 30万元,已结题,主持

2.南通市科技项目,MS2025005,池杉种子中新颖萜类聚合物的发现及α-葡萄糖苷酶抑制活性研究, 4万,在研.

科研成果：

主要从事杉科植物萜类聚合物的研究工作，对萜类以及萜类聚合物结构解析和活性有较深入的研究工作，目前已发现多个新颖骨架类化合物，主要研究成果已发表SCI论文10余篇，主要发表在Chinese Chemical Letters,Journal of Molecular Structure，Journal of Natural Products等天然产物主流期刊上，并以此为基础获得国家青年科学基金项目一项和南通市基金一项。

代表性论文：

[1] Q. Gao, X. Chong, L. Pan, Y. Xue, Y. Tang, M. Yang, J. Li, A. Wang,W.L. Wang*, G. Chen, B. Fan, 1H NMR-guided fractionation of C32-cycloartane type triterpenes from the leaves of Taxodium ascendens with anti-neuroinflammatory potential, Journal of Molecular Structure 1351 (2026).

[2] Y. Wang, P. Tang, W. Tu, Q. Gao, C. Wang, L. Tan, L. Zhao, H. Han, L. Ma, K. Otsuki, W. Xiao,W. L. Wang*, J. Liu, Y. Li, Z. Zhan, W. Li, X. Zhou, N. Li, Highly anticipated natural diterpenoids as an important source of new drugs in 2013–2023, Chinese Chemical Letters 36(1) (2025).

[3]W.L. Wang*, Q. Gao, J. Wei, J. Xiao, K. Chen, B. Lin, M. Yang, A. Wang, W. Zhu, Y. Gu, J. Li, G. Chen, B. Fan, New oligomeric terpenoids fused with an oxazoline ring linkage from cones of Taxodium ascendens and their biological activities, Journal of Molecular Structure 1321 (2025).

[4] Y.X. Li, X.J. He, Y. Chen, J.P. Gu, T.Z. Qi, H. Gu, X.Y. Zhu, M. Yang, Y.C. Gu, B. Ling, G.T. Chen,W.L. Wang*, J.L. Luo, B.Y. Fan, Controlins I-X, Resin Glycosides from the Seeds of Convolvulus tricolor and Their Biological Activities, J Nat Prod  (2025).

[5] X. Jian, G. Hong, Z. Jiaqing, X. Yuqian, C. Yunyi, Z. Weizhong, Z. Hong, F. Boyi,W. Wenli*, A Comprehensive Review of the Phytochemistry, Pharmacology and Other Applications of Euphorbiae Humifusae Herba, Molecules  (2025).

[6] J.P. Gu, T.Z. Qi, D.R. Zhu, X.J. He, S.P. Guo, X. Lan, H. Gu, J.L. Luo, M. Yang, Y.C. Gu,W.L. Wang*, G.T. Chen, B.Y. Fan, Isolation of pentasaccharide resin glycosides from the whole plants of Ipomoea biflora and their cytotoxic activities, Phytochemistry  (2025) 114494.

[7] J. Wang, W. Liu, J. Lu, M. Zhu, Y. Wu, W. Pan, B. Fan, Y. Song,W.L. Wang*, G. Chen, Antineuroinflammatory Potential of Uvaol Transformation Products by Three Fungal Species, J Agric Food Chem 72(48) (2024) 26762-26776.

[8] L. Pan, T. Zhou, C. Chen, H. Xu,W.L. Wang*, Phytochemistry, Pharmacology, and Traditional Medicine Applications of Juniperus sabina L.: A Comprehensive Overview, Molecules 29(24) (2024).

[9]W.L. Wang*, D.R. Zhu, L.N. Li, X.Q. Liu, L. Zhu, T.Y. Zhu, C. Chen, C. Han, P. Ying, Z.H. Lin, J.G. Luo, L.Y. Kong, Bioactive Dimeric Diterpenoids from Taiwania cryptomerioides (Hayata) and Their Biological Activities, Chem Biodivers  (2023) e202201067.

[10]W.L. Wang*, K.-Y. Zhang, M.-Q. Yuan, M. Yang, A.-D. Wang, L. Huang, J.L. Li, α-Glucosidase inhibitors from the husks of rice Oryza sativa L, Fitoterapia 171 (2023).

[11] X. Jiang, X.-H. Zhang, Y.-X. Li, K. Chen, B. Lin, T.-Q. Lu, M. Yang, G.-T. Chen, B.-Y. Fan,W.-L. Wang*, Chemical constituents from the leaves of Cinnamomum camphora and their α-glucosidase inhibitory activities, Phytochemistry Letters 57 (2023) 101-105.

[12] W.L. Wang*, Y. Li, Y. He, X. Jiang, Y. Yi, X. Zhang, S. Zhang, G. Chen, M. Yang, J.-L. Luo, B. Fan, Progress in the total synthesis of resin glycosides, Frontiers in Chemistry 10 (2022).

[13] Y. Lu, Y. Tang, Y. Wu, X. Zhang, Y. Yi,W.L. Wang*, A. Wang, M. Yang, B. Fan, G. Chen, Microbial transformation of betulonic acid by Circinella muscae CGMCC 3.2695 and anti-neuroinflammatory activity of the products, Phytochemistry (2022) 113431.

授权专利：

1.专利名称：二萜二聚体类化合物及其制备方法与应用

专利号：ZL 2024 1 1245022.4

2.专利名称：含有恶唑环的C30萜类聚合物类化合物及其制备方法与应用

专利号：ZL 2024 1 1245023.9