罗琳
罗琳，女，博士，教授，硕士生导师。
教育经历：
1994.09-1999.06南通医学院，临床医学，学士
2001.09-2004.06南通医学院，免疫学学，硕士
2011.09-2015.03浙江大学，药理学，博士
工作经历：
1999.08-至今 南通大学，药理学教师
2018.02-2020.07美国阿拉巴马州立大学，博士后
研究方向：
免疫药理学，中药药理学，消化系统疾病机制及治疗研究
近3年完成的基金项目：
1.国家自然科学基金委员会，面上项目，82170544,肠道炎症中转录因子Blimp1对滤泡调节性T细胞（Tfr）稳态的调控作用及机制研究，2022-01-01至2025-12-31，已结题，主持。
2.南通市科技局，基础科学研究计划，JC2020039,转录因子Blimp1调控调节性T细胞功能和代谢在肠道炎症中的作用，2020-10至2022-10，结题，主持。
3.江苏省科技厅，社会发展-面上项目, BE2018674，基于茵陈蒿汤的中药经典名方现代开发应用研究，2018-05至2022-02，结题，参与。
近5年代表性论文：
1. Ying Jiang; Xi Wang; Yinwei Zhou; Yuting Feng; Han Gu; Xingjun Liu;Lin Luo*. Transient receptor potential channels as emerging therapeutic targets: mechanisms and therapeutic insights in inflammatory bowel disease, Biochem Pharmacol, 2026, 245: 117693.
2. Chen Zhu; Ying Jiang; Yicun Liu; Zhaolian Bian*;Lin Luo*. Leucine Aminopeptidase to Spleen Length Ratio: A Novel Noninvasive Model for Predicting Esophageal Gastric Variceal Bleeding in Patients with Liver Cirrhosis. Gastroenterology Research and Practice, 2026:9637489.
3. Yihong Ji; Han Gu; Mingyue Wang; Yuanshu Miao; Chunfeng Gao; Jinlin Zhang*;Lin Luo*. Oroxylin A ameliorates hepatic steatosis and non-alcoholic fatty liver disease through the regulation of CPT1A m6A methylation in hepatocytes. Biochemistry and Biophysics Reports. 46 (2026) 102598.
4. Zhou, Yinwei; Wang, Wenbo; Gu, Han; Jiang, Ying; Wang, Xi; Su, Xin; Shao, Zhixiang; An, Kang; Liang, Rui; Ma, Yuzhen; Wang, Rui*; Luo, Lin*. Buzhongyiqi granules in ulcerative colitis Therapy: Integrated chemical composition, pharmacodynamic validation, and IL-6/STAT3 axis regulation, Journal of Ethnopharmacology, 2025, 351: 120083
5. Peng-Bo Jing, Yin-Wei Zhou, Feng-Ming Zhang, Jia-Yi Ge, Jia-Ni Wu, Jia-Huan Xu, Xiao-Hua Cao, Na Chang, Xiang Zhou,Lin Luo*, Xing-Jun Liu*. Autistic-like behaviors and impaired chronic inflammatory pain in primary nociceptive neuron-specific deletion of Mecp2 or Fmr1 knockout male mice. Behavioural Brain Research, 486 (2025): 115570
6. Qingyuan Hu, Li Zhao, Guoping Yang, Fuqiang Wen, Lihua Xie, Zuke Xiao, Feng Chen, Qing He, Tao Bian, Hao Xiong, Fangqiong Li, Yun Yue, Yaming Li,Lin Luo*, Zhu Luo*. Efficacy, pharmacokinetics, and safety of nebulized HL231 inhalation solution in patients with chronic obstructive pulmonary disease: a randomized trial. J Thorac Dis.2025; 17(10):7459-7472
7. Zhao, Lianqi; Li, Tingting; Zhou, Yinwei; Wang, Pengbo*;Luo, Lin* ; Monoclonal antibody targeting CEACAM1 enhanced the response to anti-PD1 immunotherapy in non-small cell lung cancer, International Immunopharmacology, 2024, 143: 113395.
8. Xu L, Jiang Y, Xu F, Liu J, Jiang Y, Fang F,Luo L*. Deucravacitinib and shikonin combination therapy ameliorates imiquimod-induced psoriasis in mice. Int J Immunopathol Pharmacol. 2024;38:1-16.
9. Feng Y, Wang J, Liu J, Zhou Y, Jiang Y, Zhou W, Wu F, Liu X*,Luo L*.Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice. Cells. 2024 Jun 6;13(11):988.
10.Luo L, Leavenworth JW. Analysis of the In Vivo Function of Follicular Regulatory T (TFR) Cells in the Regulation of Antibody Response. Methods Mol Biol. 2023;2559:3-13.
11. Xiaoyan Ren#, Gaoshan Zhang#, Xiang Ling, Linhua Zhang, Yangyang Tian, Guoxiang Zhu, Pengbo Wang, Jianmei W. Leavenworth,Lin Luo*, Fengzhi Li*. Allyl-isothiocyanate Against Colorectal Cancer via the Mutual Dependent Regulation of p21 and Nrf2. European Journal of Pharmacology. 2023, 957, 176016.
12. Liuliu Mao; Jun Chen; Kang Cheng; Zhihua Dou; Jonathan D. Leavenworth; Hengyue Yang; Diyuan Xu;Lin Luo*. Nrf2-Dependent Protective Effect of Paeoniflorin on α-Naphthalene Isothiocyanate-Induced Hepatic Injury, American Journal of Chinese Medicine, 2022, 5(05): 1331-1348.
13. Michael L. Dixon;Lin Luo; Sadashib Ghosh; Jefrey M. Grimes; Jonathan D. Leavenworth and Jianmei W. Leavenworth. Remodeling of the tumor microenvironment via disrupting Blimp1+ effector Treg activity augments response to anti-PD-1 blockade. Molecular Cancer,2021,20:150.
14. Zhang Z#,Luo Lin#, Xing C, Chen Y, Xu P, Li M, Zeng L, Li C, Ghosh S, Della Manna D, Townes T, Britt WJ, Wajapeyee N, Sleckman BP, Chong Z, Leavenworth JW, Yang ES. RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4 + T-cell-dependent antitumor immunity. Nature Cancer, 2021, 2(10):1018-1038.
15.Luo Lin; Hu Xianzhen; Michael Dixon; Brandon J. Pope; Jonathan D. Leavenworth; Chander Raman; William R. Meador; Jianmei W. Leavenworth. Dysregulated follicular regulatory T cells and antibody responses exacerbate experimental autoimmune encephalomyelitis, Journal of Neuroinflammation, 2021, 18(27): 1-15.