吴锋

个人简介： 

吴锋，南通大学药学院临床药理系专职教师，博士，副教授。2003年本科毕业于南通医学院，获临床医学学士学位；2015年6月研究生毕业于苏州大学药学院，获医学博士学位；2016-2018年赴美国纽约州神经发育障碍基础研究所博士后进修。主要研究领域：阿尔茨海默病及帕金森病病理机制和药物作用靶点研究。目前主持并完成国家自然科学基金一项、江苏省南通市基础研究项目四项，以第一作者或通讯作者发表学术论文二十余篇。

近三年代表性论文：

1. Z. Li, B. Tan, K. Dong, X. Yu, S.W. Zhang, L. Luo, W. Yao, Z. Qin,F. Wu*, Cobrotoxin mitigates neuroinflammation and cognitive impairment by suppressing CD8(+) T cell-microglia interactions in male 5 x FAD mice, Biochem Pharmacol 247 (2026) 117779.

2. B. Tan, J. Zhang, K. Dong, Z. Li, X. Yu, S.W. Zhang, L. Luo, W. Yao,F. Wu*, Neutrophil glycolysis mediates colitis-induced exacerbation of Alzheimer's disease, Int Immunopharmacol 171 (2026) 116127.

3. S. Li, Y. Chen, T. Song, D. Liu, R. Wu, X. Yang, Q. Wu, L. Lei, X. Yu, J. Zhang, L. Li, Y. Jiang, J. Gu, J. Miao, J.H. Gu, J. Shi,F. Wu*, F. Liu*, D. Chu*, Ganglioside sialylation modulates tau internalization and pathology spread, Mol Psychiatry  (2025).

4. W. Zhou, X. Yin, J. Huang, L. Fu, H. Yadav, W. Yao, D. Chu,F. Wu*, Verapamil modulates astrocytic glycolytic dysfunction via TXNIP inhibition in the hippocampus of 3 x Tg-AD mice, Biochem Pharmacol 242(Pt 2) (2025) 117233.

5. C. Tang, J. Wang, M. Ge, L. Fu, J. Huang, H. Yadav, J. Shi, S. Feng*,F. Wu*, DSS-induced colitis exacerbates Alzheimer's pathology via neutrophil elastase and cathepsin B activation, Int Immunopharmacol 155 (2025) 114666.

6. D. Chu, X. Yang, J. Wang, Y. Zhou, J.H. Gu, J. Miao,F. Wu*, F. Liu*, Tau truncation in the pathogenesis of Alzheimer's disease: a narrative review, Neural Regen Res 19(6) (2024) 1221-1232.

7. D. Chu, L. Lei, S. Gu, F. Liu*,F. Wu*, Dual-specificity tyrosine phosphorylation-regulated kinase 1A promotes the inclusion of amyloid precursor protein exon 7, Biochem Pharmacol 224 (2024) 116233.

8. W. Zhou, X. Yang, H. Wang, W. Yao, D. Chu*,F. Wu*, Neuronal aerobic glycolysis exacerbates synapse loss in aging mice, Exp Neurol 371 (2024) 114590.